Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 3/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL735248 | 0.89 | ADORA3 (0.43) | PRMT5WDR77ADORA3ADORA2AADORA2B | |
| SCHEMBL733570 | 0.80 | POLB (0.39) | — | |
| SCHEMBL735341 | 0.78 | ADORA3 (0.38) | PRMT5WDR77ADORA3 | |
| SCHEMBL733367 | 0.75 | TYMP (0.47) | PRMT5WDR77ADORA1 | |
| SCHEMBL733412 | 0.74 | RNMT (0.30) | — | |
| SCHEMBL733396 | 0.74 | ADORA3 (0.41) | PRMT5WDR77ADORA3ADORA2AADORA2B | |
| SCHEMBL1140221 | 0.70 | ADORA3 (0.47) | ADORA3 | |
| SCHEMBL9703679 | 0.68 | POLB (0.46) | ADORA1 | |
| SCHEMBL18927158 | 0.68 | POLB (0.46) | ADORA1 | |
| SCHEMBL17860572 | 0.68 | POLB (0.46) | ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138330-B2 | Solid phase synthesis via deblocking immobilized nucleoside, then coupling acyl protected nucleoside phosphoramidite | SIGMA-ALDRICH CO. LLC (US) | 2012-03-20 | — | — | US | disclosed |