Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | MTTP | P55157 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7513968 | 0.93 | RAB9A (0.46) | ALDH1A1F10NPC1RAB9AKCNMA1 | |
| SCHEMBL8812136 | 0.90 | SMN1; SMN2 (0.46) | ALDH1A1F10NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7371628 | 0.89 | KCNMA1 (0.48) | ALDH1A1F10NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7376165 | 0.89 | AVPR2 (0.48) | ALDH1A1F10NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7368434 | 0.86 | ALDH1A1 (0.52) | ALDH1A1F10MTTPMAPTKLK1 | |
| SCHEMBL7376652 | 0.85 | PTGER1 (0.46) | ALDH1A1F10NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7377166 | 0.82 | AVPR2 (0.48) | NPC1RAB9ASMN1; SMN2MAPTTP53 | |
| SCHEMBL7512858 | 0.81 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9ASMN1; SMN2KCNMA1 | |
| SCHEMBL7376778 | 0.80 | NPC1 (0.51) | F10NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL8813752 | 0.80 | KCNMA1 (0.49) | ALDH1A1F10NPC1SMN1; SMN2KCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |