Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.54 |
| ▸ | ADIPOR2 | Q86V24 | 1/20 | 0.54 |
| ▸ | ADIPOR1 | Q96A54 | 1/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364841 | 1.00 | SLC6A5 (0.61) | SLC6A5RAB9ANPC1POLBSMN1; SMN2 | |
| SCHEMBL7371945 | 0.94 | RAB9A (0.55) | SLC6A5RAB9ANPC1POLBSMN1; SMN2 | |
| SCHEMBL3960091 | 0.89 | SIGMAR1 (0.64) | POLBKMT2ASIGMAR1ALDH1A1 | |
| SCHEMBL3031894 | 0.81 | FAAH (0.61) | LMNAHRH3 | |
| SCHEMBL16233177 | 0.81 | SLC6A5 (0.84) | SLC6A5MEN1KMT2ASIGMAR1ADIPOR2 | |
| SCHEMBL7367718 | 0.80 | KDM2B (0.52) | RAB9ANPC1SMN1; SMN2LMNAHRH3 | |
| SCHEMBL7345278 | 0.80 | UTS2R (0.57) | RAB9ASMN1; SMN2LMNAGAA | |
| SCHEMBL7338585 | 0.80 | UTS2R (0.57) | RAB9ASMN1; SMN2LMNAGAA | |
| SCHEMBL7369861 | 0.80 | FAAH (0.62) | RAB9ANPC1SMN1; SMN2TP53MEN1 | |
| SCHEMBL7369855 | 0.80 | FAAH (0.62) | RAB9ANPC1SMN1; SMN2TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117841-A | USED TO TREAT STROKE, CEREBRAL ISCHEMIA, PAIN, HEAD TRAUMA OR EPILEPSY | WARNER-LAMBERT COMPANY (US) | 2000-09-12 | — | — | US | disclosed |
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | disclosed |