Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.46 |
| ▸ | LTA4H | P09960 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPIA | P62937 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8151298 | 0.82 | LMNA (0.46) | PPARGPPIAMAPTMAPK1 | |
| SCHEMBL7371527 | 0.82 | TBXAS1 (0.47) | TBXAS1LTA4HPPARGCYP4F2CYP4A11 | |
| SCHEMBL7369166 | 0.81 | LTA4H (0.48) | TBXAS1LTA4HPPARGCYP4F2CYP4A11 | |
| SCHEMBL7372937 | 0.78 | ALDH1A1 (0.51) | TBXAS1MAPTALDH1A1 | |
| SCHEMBL8158041 | 0.78 | PPARG (0.58) | LTA4HPPARGCYP4F2CYP4A11MAPT | |
| SCHEMBL8161951 | 0.76 | DHFR (0.51) | TBXAS1LTA4HCYP4F2CYP4A11CYP1A2 | |
| SCHEMBL16147863 | 0.76 | CYP4F2 (0.51) | TBXAS1LTA4HPPARGCYP4F2CYP4A11 | |
| SCHEMBL29852682 | 0.75 | TBXAS1 (0.46) | TBXAS1LTA4HCYSLTR2CYSLTR1 | |
| SCHEMBL12610480 | 0.75 | CNR1 (0.47) | PPARGCYP4F2CYP4A11F2RL3 | |
| SCHEMBL3956764 | 0.75 | PPARG (0.49) | TBXAS1LTA4HPPARGCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |