Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | CFD | P00746 | 2/20 | 0.47 |
| ▸ | AGER | Q15109 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10785852 | 0.88 | AGER (0.45) | KDM4EHSD17B10AGERHTTBLM | |
| SCHEMBL10353962 | 0.87 | AGER (0.44) | KDM4EHSD17B10AGERHTTBLM | |
| SCHEMBL7410882 | 0.87 | HTT (0.57) | KDM4EHSD17B10AGERHTTBLM | |
| SCHEMBL133355 | 0.86 | AGER (0.58) | KDM4EHSD17B10AGERHTTKMT2A | |
| SCHEMBL6229101 | 0.82 | ALDH1A1 (0.56) | KDM4EHSD17B10AGERKMT2ASMN1; SMN2 | |
| SCHEMBL11594600 | 0.82 | KDM4E (0.59) | KDM4EHSD17B10AGERHTTTP53 | |
| SCHEMBL16586314 | 0.80 | CFD (0.56) | KDM4EHSD17B10CFDBLMTP53 | |
| SCHEMBL10827979 | 0.80 | AGER (0.53) | KDM4EHSD17B10AGERHTTKMT2A | |
| SCHEMBL8189691 | 0.80 | PTPN1 (0.45) | KDM4EHSD17B10AGERKMT2ASMN1; SMN2 | |
| SCHEMBL10784794 | 0.79 | AGER (0.44) | KDM4EHSD17B10AGERHTTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243959-B1 | SUBSTITUTED BENZAMIDE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Dainippon Pharmaceutical Co., Ltd. (JP) | 1992-08-19 | — | — | EP | disclosed |
| US-4870074-A | Substituted benzamide derivatives, for enhancing gastrointestinal motility | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1989-09-26 | — | — | US | disclosed |
| EP-0243959-A1 | Substituted benzamide derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same | Dainippon Pharmaceutical Co., Ltd. (JP) | 1987-11-04 | — | — | EP | disclosed |
| US-4703055-A | GASTROMOTOR AGENTS; NO SIDE EFFECTS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1987-10-27 | — | — | US | disclosed |