Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.48 |
| ▸ | ANPEP | P15144 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365391 | 0.91 | AGTR2 (0.44) | LNPEPANPEPCA2CA1AGTR2 | |
| SCHEMBL7444103 | 0.91 | AGTR2 (0.44) | LNPEPANPEPCA2CA1AGTR2 | |
| SCHEMBL7370637 | 0.83 | AGTR2 (0.48) | LNPEPANPEPCA2CA1AGTR2 | |
| SCHEMBL7365722 | 0.75 | LNPEP (0.49) | LNPEPANPEPCA2CA1AGTR2 | |
| SCHEMBL7403012 | 0.72 | LNPEP (0.62) | LNPEPANPEPCA2CA1 | |
| SCHEMBL8803228 | 0.72 | CYP2C9 (0.40) | ANPEPCA2CA1AGTR2KMT2A | |
| SCHEMBL7405758 | 0.69 | LNPEP (0.59) | LNPEPANPEPCA2CA1AGTR2 | |
| SCHEMBL7548954 | 0.69 | LNPEP (0.59) | LNPEPANPEPCA2CA1AGTR2 | |
| SCHEMBL7400488 | 0.69 | LNPEP (0.59) | LNPEPANPEPCA2CA1AGTR2 | |
| SCHEMBL7401025 | 0.69 | LNPEP (0.59) | LNPEPANPEPCA2CA1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920307-A2 | DERIVATES FROM BISARYLTETRACARBONACID, AND PHARMARCEUTICAL PRODUCT CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998006386-A2 | DERIVATES FROM BISARYLTETRACARBONACID, AND PHARMARCEUTICAL PRODUCT CONTAINING THEM | ROCHE DIAGNOSTICS GMBH (DE) | 1998-02-19 | — | — | WO | disclosed |