Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 3/20 | 0.48 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.47 |
| ▸ | ANPEP | P15144 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365391 | 0.94 | AGTR2 (0.44) | AGTR2LNPEPANPEPCA2CA1 | |
| SCHEMBL7444103 | 0.94 | AGTR2 (0.44) | AGTR2LNPEPANPEPCA2CA1 | |
| SCHEMBL7365722 | 0.90 | LNPEP (0.49) | AGTR2LNPEPANPEPCA2CA1 | |
| SCHEMBL7369023 | 0.83 | LNPEP (0.48) | AGTR2LNPEPANPEPCA2CA1 | |
| SCHEMBL7368170 | 0.81 | PTPN1 (0.53) | AGTR2CA2CA1MEN1KMT2A | |
| SCHEMBL7364482 | 0.81 | LNPEP (0.37) | AGTR2LNPEPANPEPMEN1KMT2A | |
| SCHEMBL7369936 | 0.77 | PTPN1 (0.51) | AGTR2CA2CA1 | |
| SCHEMBL7548954 | 0.75 | LNPEP (0.59) | AGTR2LNPEPANPEPCA2CA1 | |
| SCHEMBL7400488 | 0.75 | LNPEP (0.59) | AGTR2LNPEPANPEPCA2CA1 | |
| SCHEMBL7401025 | 0.75 | LNPEP (0.59) | AGTR2LNPEPANPEPCA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920307-A2 | DERIVATES FROM BISARYLTETRACARBONACID, AND PHARMARCEUTICAL PRODUCT CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998006386-A2 | DERIVATES FROM BISARYLTETRACARBONACID, AND PHARMARCEUTICAL PRODUCT CONTAINING THEM | ROCHE DIAGNOSTICS GMBH (DE) | 1998-02-19 | — | — | WO | disclosed |