Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.39 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364168 | 0.90 | PRSS1 (0.40) | TEAD1TEAD3BCHEMAOAACHE | |
| SCHEMBL6164707 | 0.78 | CYP1A2 (0.45) | LMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL6166317 | 0.78 | AOC3 (0.42) | LMNAGAAMEN1ALDH1A1KMT2A | |
| SCHEMBL6160629 | 0.74 | DPP4 (0.40) | MEN1KMT2A | |
| SCHEMBL7360351 | 0.71 | PARP14 (0.40) | TEAD1TPSAB1TPSD1TPSG1GAA | |
| SCHEMBL7365919 | 0.71 | GRIN2D (0.36) | TEAD1TEAD3LMNAPARP14GRIN2D | |
| SCHEMBL7363740 | 0.71 | GRIN2D (0.44) | PRSS1PRSS2PRSS3F2TPSAB1 | |
| SCHEMBL7361819 | 0.71 | VNN1 (0.38) | TEAD1TPSAB1TPSD1TPSG1LMNA | |
| SCHEMBL4086461 | 0.70 | ADRB2 (0.41) | PRSS1F2TPSAB1TPSD1TPSG1 | |
| SCHEMBL7365153 | 0.70 | LMNA (0.36) | TEAD1TEAD3MAOBPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |