Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.34 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363740 | 0.90 | GRIN2D (0.44) | VNN1LMNAGAALTA4HITGB3 | |
| SCHEMBL7364589 | 0.84 | ALDH1A1 (0.50) | LMNADPP4DPP8DPP9DPP7 | |
| SCHEMBL15650145 | 0.76 | GFER (0.49) | LMNAGAAKDM4EMAPT | |
| SCHEMBL7365927 | 0.73 | GRIN2D (0.46) | LMNAGAAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL7361150 | 0.73 | FAAH (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL4096230 | 0.73 | TPSAB1 (0.43) | GRIN2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL3145712 | 0.72 | SIGMAR1 (0.44) | CCR3LTA4HTEAD1 | |
| SCHEMBL7364168 | 0.72 | PRSS1 (0.40) | LMNAGAATPSAB1TPSD1TPSG1 | |
| SCHEMBL7360351 | 0.72 | PARP14 (0.40) | GAAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28757734 | 0.71 | CACNA1B (0.50) | LMNAGAADPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |