Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 6/20 | 0.33 |
| ▸ | NAMPT | P43490 | 3/20 | 0.32 |
| ▸ | PPIA | P62937 | 2/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.32 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | LATS1 | O95835 | 2/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373241 | 1.00 | HPGDS (0.34) | HPGDSAKT1NAMPTPPIAROCK2 | |
| SCHEMBL7422899 | 0.89 | HPGDS (0.34) | HPGDSAKT1NAMPTPPIAROCK2 | |
| SCHEMBL7373193 | 0.85 | AKT1 (0.37) | HPGDSAKT1NAMPTROCK2LATS1 | |
| SCHEMBL7377427 | 0.79 | HPGDS (0.31) | HPGDS | |
| SCHEMBL7376594 | 0.79 | ROCK2 (0.42) | AKT1PPIAROCK2 | |
| SCHEMBL7374405 | 0.78 | AKT1 (0.35) | HPGDSAKT1NAMPTROCK2LATS1 | |
| SCHEMBL7378233 | 0.73 | AKT1 (0.36) | AKT1ROCK2 | |
| SCHEMBL7369928 | 0.71 | ROCK2 (0.41) | AKT1PPIAROCK2 | |
| SCHEMBL7367861 | 0.70 | ROCK2 (0.40) | AKT1PPIAROCK2 | |
| SCHEMBL7383670 | 0.69 | F10 (0.41) | AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086099-A4 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARM PROD INC (US) | 2002-01-02 | — | — | EP | disclosed |
| EP-0944386-A4 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARM PROD INC (US) | 2001-04-11 | — | — | EP | disclosed |
| EP-1086099-A1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | Aventis Pharmaceuticals Products Inc. (US) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999062904-A1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 1999-12-09 | — | — | WO | disclosed |
| EP-0944386-A1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998025611-A1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-06-18 | — | — | WO | disclosed |