Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 7/20 | 0.33 |
| ▸ | AKT1 | P31749 | 3/20 | 0.33 |
| ▸ | NAMPT | P43490 | 4/20 | 0.32 |
| ▸ | PPIA | P62937 | 2/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | LATS1 | O95835 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369599 | 0.89 | HPGDS (0.34) | HPGDSROCK2AKT1NAMPTPPIA | |
| SCHEMBL7373241 | 0.89 | HPGDS (0.34) | HPGDSROCK2AKT1NAMPTPPIA | |
| SCHEMBL7374405 | 0.85 | AKT1 (0.35) | HPGDSROCK2AKT1NAMPTLATS1 | |
| SCHEMBL7369928 | 0.82 | ROCK2 (0.41) | ROCK2AKT1PPIA | |
| SCHEMBL7373193 | 0.78 | AKT1 (0.37) | HPGDSROCK2AKT1NAMPTLATS1 | |
| Trifluoroacetic Acid SCHEMBL7376828 | 0.77 | AKT1 (0.33) | ROCK2AKT1ROCK1 | |
| Trifluoroacetic Acid SCHEMBL7384596 | 0.73 | ROCK2 (0.36) | HPGDSROCK2NAMPT | |
| SCHEMBL7377427 | 0.72 | HPGDS (0.31) | HPGDS | |
| SCHEMBL7367861 | 0.70 | ROCK2 (0.40) | ROCK2AKT1PPIA | |
| SCHEMBL16246731 | 0.70 | ROCK2 (0.44) | ROCK2AKT1NR3C1ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975600-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS | Akzo Nobel N.V. (NL) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998047876-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS | AKZO NOBEL N.V. (NL) | 1998-10-29 | — | — | WO | disclosed |