Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.49 |
| ▸ | ATR | Q13535 | 1/20 | 0.48 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370856 | 0.84 | NPY5R (0.47) | ALDH1A1HPGDHSD17B10NPY5RATR | |
| SCHEMBL7370913 | 0.81 | NPY5R (0.57) | ALDH1A1HPGDHSD17B10CYP11B1CYP11B2 | |
| SCHEMBL7372225 | 0.80 | NPY5R (0.62) | CYP11B1CYP11B2NPY5RMKNK1MKNK2 | |
| SCHEMBL7369602 | 0.80 | NPY5R (0.56) | CYP11B1CYP11B2NPY5RMKNK1MKNK2 | |
| SCHEMBL7371445 | 0.79 | NPY5R (0.67) | ALDH1A1NPY5RMEN1KMT2APDGFRB | |
| SCHEMBL7377111 | 0.79 | NPY5R (0.54) | CYP11B1CYP11B2NPY5RMKNK1MKNK2 | |
| SCHEMBL23758267 | 0.77 | SMPD3 (0.48) | ALDH1A1HPGDHSD17B10KDRMEN1 | |
| SCHEMBL7367135 | 0.77 | CYP11B1 (0.52) | ALDH1A1HPGDHSD17B10CYP11B1CYP11B2 | |
| SCHEMBL7370879 | 0.76 | NPY5R (0.59) | CYP11B1CYP11B2NPY5RMKNK1MKNK2 | |
| SCHEMBL7365692 | 0.75 | NPY5R (0.57) | ALDH1A1HPGDHSD17B10CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |