Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370428 | 0.92 | ALDH1A1 (0.62) | KDM4EMEN1KMT2ATP53MAPK1 | |
| SCHEMBL7370205 | 0.92 | CCR1 (0.56) | KDM4EMEN1KMT2ATP53MAPK1 | |
| SCHEMBL8545193 | 0.91 | KDM4E (0.54) | KDM4EMEN1KMT2ATP53MAPK1 | |
| SCHEMBL5061535 | 0.87 | CCR1 (0.56) | KDM4EMEN1KMT2ATP53MAPK1 | |
| SCHEMBL5063868 | 0.87 | CCR1 (0.56) | KDM4EMEN1KMT2ATP53MAPK1 | |
| SCHEMBL7366950 | 0.84 | SMN1; SMN2 (0.55) | KDM4EMEN1KMT2ATP53MAPK1 | |
| SCHEMBL7370866 | 0.84 | KDM4E (0.58) | KDM4EMEN1KMT2ATP53MAPK1 | |
| SCHEMBL5064235 | 0.83 | CCR1 (0.58) | KDM4EMEN1KMT2ATP53MAPK1 | |
| SCHEMBL5064511 | 0.81 | CCR1 (0.55) | KDM4EMEN1KMT2ATP53MAPK1 | |
| SCHEMBL7373089 | 0.81 | CACNA1F (0.55) | KDM4EMEN1KMT2ATP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706517-B1 | PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY | NISSAN CHEMICAL IND LTD (JP) | 1998-10-21 | — | — | EP | disclosed |
| EP-0706517-A1 | PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001343-A1 | PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1995-01-12 | — | — | WO | disclosed |