Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369950 | 0.91 | KDM4E (0.55) | KDM4EKMT2AMEN1TP53MAPK1 | |
| SCHEMBL7370205 | 0.91 | CCR1 (0.56) | KDM4EKMT2AMEN1TP53MAPK1 | |
| SCHEMBL7370428 | 0.91 | ALDH1A1 (0.62) | KDM4EKMT2AMEN1TP53MAPK1 | |
| SCHEMBL5063868 | 0.86 | CCR1 (0.56) | KDM4EKMT2AMEN1TP53MAPK1 | |
| SCHEMBL8545712 | 0.85 | ALDH1A1 (0.50) | TP53MAPK1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL7366950 | 0.83 | SMN1; SMN2 (0.55) | KDM4EKMT2AMEN1TP53MAPK1 | |
| SCHEMBL7370866 | 0.83 | KDM4E (0.58) | KDM4EKMT2AMEN1TP53MAPK1 | |
| SCHEMBL5061294 | 0.82 | KDM4E (0.51) | KDM4EKMT2AMEN1TP53MAPK1 | |
| SCHEMBL5061292 | 0.82 | KDM4E (0.51) | KDM4EKMT2AMEN1TP53MAPK1 | |
| SCHEMBL5064235 | 0.82 | CCR1 (0.58) | KDM4EKMT2AMEN1TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706517-B1 | PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY | NISSAN CHEMICAL IND LTD (JP) | 1998-10-21 | — | — | EP | disclosed |