Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 4/20 | 0.53 |
| ▸ | SKP2 | Q13309 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366050 | 0.86 | CKS1B (0.47) | CKS1BSKP2PTGS2EDNRA | |
| SCHEMBL7371551 | 0.77 | LMNA (0.54) | CKS1BSKP2LMNACA12CA2 | |
| SCHEMBL7376096 | 0.75 | KDM4E (0.49) | ALDH1A1CYP2C9CYP2C19SMN1; SMN2KDM4E | |
| SCHEMBL28402292 | 0.75 | NAMPT (0.60) | CKS1BSKP2LMNACA12CA2 | |
| SCHEMBL7368714 | 0.74 | IKBKB (0.48) | LMNAALDH1A1MAPTCYP2C9CYP2C19 | |
| SCHEMBL28766867 | 0.74 | PTGS2 (0.43) | POLBSMN1; SMN2KMT2AKDM4EMEN1 | |
| SCHEMBL7368966 | 0.73 | NPC1 (0.46) | ALDH1A1MAPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL7372407 | 0.73 | LMNA (0.49) | LMNAALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL7372680 | 0.73 | MAPK1 (0.48) | LMNAALDH1A1POLBMAPTCYP2C9 | |
| SCHEMBL23057275 | 0.73 | NAMPT (0.53) | CKS1BSKP2LMNACA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |