Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 6/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7512593 | 0.92 | CYP19A1 (0.45) | MTTPCYP19A1HTTLRRK2MAPT | |
| SCHEMBL7749370 | 0.90 | CYP19A1 (0.49) | CYP19A1LRRK2PTGER1AVPR2 | |
| SCHEMBL7372395 | 0.88 | MTTP (0.43) | MTTPHTTPOLBNPC1AHR | |
| SCHEMBL7367409 | 0.87 | HTT (0.47) | MTTPHTTPOLBMAPTNPC1 | |
| SCHEMBL7375499 | 0.87 | MTTP (0.47) | MTTPCYP19A1POLBMAPTPTGER1 | |
| SCHEMBL7376314 | 0.85 | MTTP (0.42) | MTTPHTTPOLBMAPTNPC1 | |
| SCHEMBL8816546 | 0.84 | CYP19A1 (0.45) | CYP19A1HTTLRRK2MAPTPTGER1 | |
| SCHEMBL7376652 | 0.84 | PTGER1 (0.46) | MTTPCYP19A1HTTMAPTPTGER1 | |
| SCHEMBL7371809 | 0.84 | PTGER1 (0.46) | CYP19A1HTTMAPTPTGER1NPC1 | |
| SCHEMBL7375995 | 0.83 | CYP19A1 (0.51) | CYP19A1LRRK2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |