Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 7/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375995 | 0.93 | CYP19A1 (0.51) | CYP19A1LRRK2GAASGMS2 | |
| SCHEMBL7512593 | 0.91 | CYP19A1 (0.45) | CYP19A1PTGER1LRRK2AVPR2AVPR1A | |
| SCHEMBL7376652 | 0.90 | PTGER1 (0.46) | CYP19A1PTGER1 | |
| SCHEMBL7371809 | 0.90 | PTGER1 (0.46) | CYP19A1PTGER1 | |
| SCHEMBL7370837 | 0.90 | MTTP (0.48) | CYP19A1PTGER1LRRK2AVPR2 | |
| SCHEMBL7375499 | 0.89 | MTTP (0.47) | CYP19A1PTGER1AVPR2 | |
| SCHEMBL7378156 | 0.88 | LRRK2 (0.48) | CYP19A1PTGER1LRRK2GAASGMS2 | |
| SCHEMBL7371570 | 0.87 | MEN1 (0.46) | AVPR2AVPR1A | |
| SCHEMBL7374553 | 0.85 | MEN1 (0.48) | CYP19A1 | |
| SCHEMBL7376600 | 0.85 | RXRA (0.48) | CYP19A1PTGER1GAASGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |