Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367075 | 0.86 | NPY5R (0.48) | NPY5RKDM4ELMNAALDH1A1MEN1 | |
| SCHEMBL7376649 | 0.86 | POLB (0.47) | NPY5RHTTP2RX7ALDH1A1MAPT | |
| SCHEMBL7369586 | 0.84 | ROS1 (0.47) | KDM4ELMNACYP11B1CYP11B2MAOA | |
| SCHEMBL7372122 | 0.80 | CYP11B1 (0.46) | MEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL7369883 | 0.80 | CYP11B1 (0.46) | KDM4EHPGDMEN1KMT2ACYP11B1 | |
| SCHEMBL7372407 | 0.79 | LMNA (0.49) | NPY5RKDM4ELMNAP2RX7ALDH1A1 | |
| SCHEMBL7370741 | 0.79 | MAPT (0.54) | NPY5RKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL7372671 | 0.78 | KDM4E (0.46) | KDM4EALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL7371087 | 0.77 | NPC1 (0.43) | KDM4EHTTALDH1A1HPGDMEN1 | |
| SCHEMBL7373609 | 0.77 | MAPT (0.44) | KDM4ELMNAALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| CN-87105680-A | Imidazolium compounds and preparation method thereof and comprise the pharmaceutical composition of this compound | — | 1988-04-27 | — | — | CN | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |