Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7372694 | 0.85 | CYP1A2 (0.43) | ALOX5PDE10ADAOADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL8388746 | 0.71 | CYP1A2 (0.46) | KDM4EDAO | |
| SCHEMBL8957153 | 0.71 | MMP2 (0.44) | KDM4EALDH1A1LMNADAO | |
| SCHEMBL5260106 | 0.70 | KDM4E (0.48) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL6801737 | 0.69 | GABRA1 (0.47) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| Hydrochloric Acid SCHEMBL6984470 | 0.69 | KDM4E (0.47) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL1694910 | 0.69 | SLC6A2 (0.45) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL12315105 | 0.68 | TNF (0.47) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL8469059 | 0.67 | PPARG (0.56) | ALDH1A1GAATACR1 | |
| SCHEMBL3800271 | 0.67 | GAA (0.56) | MEN1NPC1ALDH1A1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073638-A1 | HETEROCYCLICALLY SUBSTITUTED AMIDES, THEIR PRODUCTION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999054304-A1 | HETEROCYCLICALLY SUBSTITUTED AMIDES, THEIR PRODUCTION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-28 | — | — | WO | disclosed |