Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP14 | P54578 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30897522 | 0.72 | IL6 (0.39) | — | |
| SCHEMBL31430559 | 0.72 | IL6 (0.39) | — | |
| SCHEMBL31317095 | 0.71 | USP14 (0.33) | USP14 | |
| SCHEMBL30079928 | 0.70 | USP14 (0.35) | USP14 | |
| SCHEMBL27739740 | 0.70 | ALDH1A1 (0.41) | — | |
| SCHEMBL6411255 | 0.69 | NPC1 (0.36) | — | |
| SCHEMBL15062755 | 0.69 | LPL (0.37) | — | |
| SCHEMBL4496052 | 0.69 | PREP (0.48) | CA12CA1CA9 | |
| SCHEMBL12855670 | 0.69 | AGXT (0.52) | USP14CA1CA9 | |
| SCHEMBL906834 | 0.69 | IDO1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164371-A | HETEROCYCLIC KETONES | ICI AMERICAS INC. (US) | 1992-11-17 | — | — | US | disclosed |
| EP-0291234-A2 | Peptidic human leukocyte elastase (HLE) inhibitors | ZENECA INC. (US) | 1988-11-17 | — | — | EP | disclosed |