Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 5/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.54 |
| ▸ | ELANE | P08246 | 2/20 | 0.53 |
| ▸ | CTSS | P25774 | 5/20 | 0.52 |
| ▸ | CTSL | P07711 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8427301 | 0.86 | ATM (0.52) | ALDH1A1ATMCTSKCTRB1ELANE | |
| SCHEMBL7372298 | 0.86 | ATM (0.61) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL9112663 | 0.85 | ATM (0.54) | ALDH1A1ATMCTSKCTRB1ELANE | |
| SCHEMBL28088130 | 0.85 | TSHR (0.58) | ALDH1A1ATMCTSKCTRB1ELANE | |
| SCHEMBL28088128 | 0.85 | TSHR (0.58) | ALDH1A1ATMCTSKCTRB1ELANE | |
| SCHEMBL10861784 | 0.84 | ALDH1A1 (0.56) | ALDH1A1ATMCTSKCTRB1ELANE | |
| SCHEMBL10420900 | 0.83 | CTSL (0.54) | ALDH1A1ATMCTSKCTRB1ELANE | |
| SCHEMBL10420899 | 0.83 | CTSL (0.54) | ALDH1A1ATMCTSKCTRB1ELANE | |
| SCHEMBL10519875 | 0.82 | ALDH1A1 (0.56) | ALDH1A1ATMCTSKCTRB1ELANE | |
| SCHEMBL27648023 | 0.82 | CTSK (0.56) | ALDH1A1ATMCTSKCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659188-A4 | METHODS FOR THE SYNTHESIS OF PHOSPHONATE ESTERS. | AFFYMAX TECH NV (AN) | 1995-11-22 | — | — | EP | disclosed |
| EP-0659188-A1 | METHODS FOR THE SYNTHESIS OF PHOSPHONATE ESTERS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1995-06-28 | — | — | EP | disclosed |
| US-5420328-A | Esterification with alcohol and hydrolysis | AFFYMAX TECHNOLOGIES, N.V. (AN) | 1995-05-30 | — | — | US | disclosed |
| US-5359115-A | Reacting phosphonic monoester with dialkylazodicarboxylate, triphenylphosphine and secondary alcohol to form diester, hydrolyzing selective ester to form monoester, coupling an aminoacid to yield peptidylphosphonate | AFFYMAX TECHNOLOGIES, N.V. (US) | 1994-10-25 | — | — | US | disclosed |
| WO-1994006808-A1 | METHODS FOR THE SYNTHESIS OF PHOSPHONATE ESTERS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1994-03-31 | — | — | WO | disclosed |
| US-4457924-A | PENICILLINS, OXAPENICILLINS, BETA-LACTAMASE INHIBITORS | PFIZER, INC. (US) | 1984-07-03 | — | — | US | disclosed |
| EP-0083484-A1 | 1,1-Alkanediol dicarboxylate linked antibacterial agents | PFIZER INC. (US) | 1983-07-13 | — | — | EP | disclosed |