Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373236 | 1.00 | TSHR (0.39) | TSHRSLC2A1PLA2G2AALDH1A1HSD17B10 | |
| SCHEMBL6422006 | 0.83 | ALDH1A1 (0.37) | ALDH1A1HSD17B10HDAC3HDAC1MTNR1A | |
| SCHEMBL6422010 | 0.83 | ALDH1A1 (0.37) | ALDH1A1HSD17B10HDAC3HDAC1MTNR1A | |
| SCHEMBL6898655 | 0.74 | ALDH1A1 (0.37) | TSHRALDH1A1HSD17B10MTNR1AMTNR1B | |
| SCHEMBL324198 | 0.68 | APEX1 (0.48) | MTNR1ACNR1 | |
| SCHEMBL8436475 | 0.67 | ALOX5 (0.43) | TSHRALDH1A1CNR1 | |
| SCHEMBL7617840 | 0.67 | GSK3B (0.50) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7934147 | 0.67 | GSK3B (0.50) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL4639106 | 0.65 | ALDH1A1 (0.34) | ALDH1A1HSD17B10 | |
| SCHEMBL4639101 | 0.65 | ALDH1A1 (0.34) | ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023073-A1 | VITRONECTIN RECEPTOR ANTAGONIST | SMITHKLINE BEECHAM CORPORATION (US) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999015178-A1 | VITRONECTIN RECEPTOR ANTAGONIST | SMITHKLINE BEECHAM CORPORATION (US) | 1999-04-01 | — | — | WO | disclosed |