Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442464 | 0.80 | SYK (0.42) | HTR2CHTR2BRAB9A | |
| SCHEMBL7366435 | 0.77 | MBTPS1 (0.47) | ALOX5HTR2CHTR2BTRPM8KCNH2 | |
| SCHEMBL7368517 | 0.77 | CACNA1B (0.47) | ALOX5KCNH2PARP10 | |
| SCHEMBL7370864 | 0.75 | MBTPS1 (0.52) | ALOX5KCNH2 | |
| SCHEMBL3183974 | 0.70 | HTR2C (0.49) | HTR2CHTR2B | |
| SCHEMBL7372181 | 0.69 | ALOX5 (0.51) | ALOX5L3MBTL1PARP10 | |
| SCHEMBL2170633 | 0.67 | ALOX5 (0.67) | ALOX5RAB9APARP10 | |
| SCHEMBL7369242 | 0.67 | DPP7 (0.59) | ALOX5RAB9APARP10 | |
| SCHEMBL7761599 | 0.66 | NR4A1 (0.62) | ALOX5PARP10 | |
| SCHEMBL14014011 | 0.66 | LTA4H (0.48) | ALOX5RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | claimed |
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | disclosed |