Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 11/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 11/20 | 0.42 |
| ▸ | PLAU | P00749 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371376 | 1.00 | CASP3 (0.50) | CASP3HCRTR1HCRTR2PLAULMNA | |
| SCHEMBL7372575 | 0.92 | CASP3 (0.50) | CASP3HCRTR1HCRTR2PLAULMNA | |
| SCHEMBL7380965 | 0.88 | PLAU (0.53) | HCRTR1HCRTR2PLAULMNARECQL | |
| SCHEMBL7365364 | 0.87 | PLAU (0.54) | HCRTR1HCRTR2PLAULMNARECQL | |
| Hydrochloric Acid SCHEMBL7368609 | 0.87 | PLAU (0.53) | HCRTR1HCRTR2PLAULMNARECQL | |
| Hydrochloric Acid SCHEMBL7366142 | 0.87 | PLAU (0.53) | HCRTR1HCRTR2PLAULMNARECQL | |
| SCHEMBL7370379 | 0.85 | PLAU (0.54) | HCRTR1HCRTR2PLAULMNARECQL | |
| Hydrochloric Acid SCHEMBL7369169 | 0.84 | PLAU (0.54) | HCRTR1HCRTR2PLAULMNARECQL | |
| Hydrochloric Acid SCHEMBL7369946 | 0.84 | PLAU (0.54) | HCRTR1HCRTR2PLAULMNARECQL | |
| SCHEMBL7368857 | 0.83 | LMNA (0.45) | HCRTR1HCRTR2PLAULMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242120-A2 | COMBINATIONS OF GROWTH FACTORS AND I:UPA OR I:MMP FOR THE TREATMENT OF DAMAGED TISSUE | Pfizer Limited (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001049309-A2 | COMBINATIONS OF GROWTH FACTORS AND I: UPA OR I: MMP FOR THE TREATMENT OF DAMAGED TISSUE | PFIZER LIMITED (GB) | 2001-07-12 | — | — | WO | disclosed |
| EP-1077945-A1 | ISOQUINOLINES AS UROKINASE INHIBITORS | PFIZER INC. (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-2000005214-A2 | ISOQUINOLINES AS UROKINASE INHIBITORS | PFIZER INC. (US) | 2000-02-03 | — | — | WO | disclosed |