Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7372959 | 0.81 | ALDH1A1 (0.45) | CA2ALDH1A1LMNACA1L3MBTL1 | |
| SCHEMBL382142 | 0.79 | SMN1; SMN2 (0.44) | CA2SMN1; SMN2CA1CA12CA9 | |
| SCHEMBL7651608 | 0.79 | SMN1; SMN2 (0.44) | CA2SMN1; SMN2CA1CA12CA9 | |
| SCHEMBL9094518 | 0.78 | CA2 (0.41) | CA2ALDH1A1CA1CA12CA9 | |
| SCHEMBL7372099 | 0.78 | NPC1 (0.45) | CA2ALDH1A1CA1KDM4ECA12 | |
| Hydrochloric Acid SCHEMBL382912 | 0.78 | SMN1; SMN2 (0.43) | CA2SMN1; SMN2CA1CA12CA9 | |
| SCHEMBL7452279 | 0.78 | CYP2C9 (0.42) | CA2ALDH1A1CNR2SMN1; SMN2LMNA | |
| SCHEMBL7378971 | 0.78 | MMP13 (0.49) | CA2ALDH1A1CA1 | |
| SCHEMBL8619624 | 0.76 | KIF11 (0.44) | CA2ALDH1A1CNR2CA1CA12 | |
| SCHEMBL16186194 | 0.72 | CA2 (0.60) | CA2ALDH1A1CNR2SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730590-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-11 | — | — | EP | claimed |
| WO-1995014683-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-06-01 | — | — | WO | claimed |