Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GALR2 | O43603 | 1/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | CCR6 | P51684 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.44 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275629 | 0.94 | SLC9A1 (0.68) | SLC9A1NPSR1ALDH1A1LMNAGALR2 | |
| SCHEMBL3915677 | 0.88 | SLC9A1 (0.51) | SLC9A1NPSR1ALDH1A1LMNAGALR2 | |
| SCHEMBL8611539 | 0.86 | SLC9A1 (0.64) | SLC9A1NPSR1ALDH1A1LMNAGALR2 | |
| SCHEMBL7474176 | 0.86 | LMNA (0.60) | SLC9A1NPSR1ALDH1A1LMNAGALR2 | |
| SCHEMBL6354726 | 0.84 | SLC9A1 (0.59) | SLC9A1NPSR1ALDH1A1LMNAGALR2 | |
| SCHEMBL23070353 | 0.84 | SMN1; SMN2 (0.57) | SLC9A1NPSR1ALDH1A1LMNAGALR2 | |
| SCHEMBL28544472 | 0.82 | SMN1; SMN2 (0.52) | SLC9A1NPSR1ALDH1A1LMNAGALR2 | |
| SCHEMBL6816581 | 0.82 | CXCR2 (0.63) | SLC9A1NPSR1ALDH1A1LMNAGALR2 | |
| SCHEMBL2972082 | 0.82 | SLC9A1 (0.60) | SLC9A1NPSR1ALDH1A1LMNAGALR2 | |
| SCHEMBL29386167 | 0.81 | SLC9A1 (0.63) | SLC9A1NPSR1ALDH1A1LMNAGALR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243959-B1 | SUBSTITUTED BENZAMIDE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Dainippon Pharmaceutical Co., Ltd. (JP) | 1992-08-19 | — | — | EP | disclosed |
| US-4870074-A | Substituted benzamide derivatives, for enhancing gastrointestinal motility | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1989-09-26 | — | — | US | disclosed |
| EP-0243959-A1 | Substituted benzamide derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same | Dainippon Pharmaceutical Co., Ltd. (JP) | 1987-11-04 | — | — | EP | disclosed |