Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 9/20 | 0.34 |
| ▸ | F2 | P00734 | 7/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7383810 | 0.89 | NOS1 (0.42) | MMP2MMP13F10F2NOS1 | |
| Trifluoroacetic Acid SCHEMBL7384671 | 0.84 | NOS1 (0.37) | SMN1; SMN2F10F2NOS1MTNR1A | |
| SCHEMBL7381960 | 0.80 | LMNA (0.41) | ALDH1A1LMNASMN1; SMN2MMP2MMP13 | |
| Trifluoroacetic Acid SCHEMBL7382209 | 0.75 | F10 (0.61) | F10F2KLK6 | |
| Trifluoroacetic Acid SCHEMBL7374889 | 0.74 | NOS1 (0.46) | F10F2NOS1 | |
| Trifluoroacetic Acid SCHEMBL7417460 | 0.71 | F10 (0.60) | F10F2 | |
| SCHEMBL7418220 | 0.71 | F10 (0.44) | MMP2MMP13F10F2 | |
| SCHEMBL7383214 | 0.71 | LMNA (0.44) | LMNAMMP2MMP13F10F2 | |
| Trifluoroacetic Acid SCHEMBL7370015 | 0.70 | MMP2 (0.35) | MMP2MMP13F10F2KLK6 | |
| Trifluoroacetic Acid SCHEMBL7373673 | 0.70 | BACE1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944386-A4 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARM PROD INC (US) | 2001-04-11 | — | — | EP | disclosed |
| EP-0944386-A1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998025611-A1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-06-18 | — | — | WO | disclosed |