Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 4/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | DAO | P14920 | 2/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6958143 | 0.90 | HTR2B (0.49) | HTR2BHTR3APPARGDAOCA12 | |
| SCHEMBL11787842 | 0.83 | ALDH1A1 (0.45) | HTR2BHTR3ADAOGPR84CA12 | |
| SCHEMBL6954657 | 0.82 | SMN1; SMN2 (0.44) | HTR2BHTR3ADAOGPR84CA12 | |
| SCHEMBL6960622 | 0.82 | SMN1; SMN2 (0.49) | PPARGGPR84CA12CA1CA2 | |
| SCHEMBL8538683 | 0.81 | KMT2A (0.39) | HTR2BHTR3ADAOGPR84CA12 | |
| SCHEMBL6956148 | 0.79 | PTGES (0.45) | GPR84CA12CA1CA2HSD17B3 | |
| SCHEMBL6959678 | 0.78 | SMN1; SMN2 (0.42) | HTR2BHTR3AGPR84CA12CA1 | |
| SCHEMBL6950945 | 0.77 | GSK3B (0.47) | GPR84 | |
| SCHEMBL9041438 | 0.77 | GPR84 (0.39) | HTR2BHTR3ADAOGPR84CA12 | |
| SCHEMBL6952786 | 0.77 | L3MBTL1 (0.39) | HTR2BHTR3ADAOGPR84CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729465-A1 | PYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE, DAVIS & COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995014013-A1 | PYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE, DAVIS & COMPANY (US) | 1995-05-26 | — | — | WO | disclosed |