Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ME3 | Q16798 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8143555 | 0.86 | ALDH1A1 (0.48) | ALDH1A1ME3ABL1MAPK1MAPT | |
| Trifluoroacetic Acid SCHEMBL7376343 | 0.85 | ME3 (0.48) | ALDH1A1ME3ABL1MAPK1DEGS1 | |
| SCHEMBL7370662 | 0.84 | PTPN2 (0.51) | ALDH1A1ME3ABL1MAPK1MAPT | |
| SCHEMBL8135054 | 0.83 | LMNA (0.49) | ALDH1A1ME3ABL1MAPK1MAPT | |
| SCHEMBL7371765 | 0.82 | ME3 (0.54) | ALDH1A1ME3ABL1MAPK1MAPT | |
| SCHEMBL533096 | 0.80 | ALDH1A1 (0.62) | ALDH1A1ME3ABL1MAPTMEN1 | |
| SCHEMBL8134089 | 0.79 | ALDH1A1 (0.47) | ALDH1A1ME3ABL1MAPTMEN1 | |
| SCHEMBL8141352 | 0.76 | ME3 (0.52) | ALDH1A1ME3ABL1MAPK1MAPT | |
| Acetic Acid SCHEMBL8135057 | 0.76 | ME3 (0.52) | ALDH1A1ME3ABL1MAPK1MAPT | |
| SCHEMBL7374819 | 0.75 | ALDH1A1 (0.50) | ALDH1A1ME3ABL1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069143-A | Fibrinogen receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-30 | — | — | US | disclosed |
| EP-0885213-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0885213-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997025323-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-17 | — | — | WO | disclosed |