Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ME3 | Q16798 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374819 | 0.88 | ALDH1A1 (0.50) | ALDH1A1ME3ABL1MAPTHTT | |
| SCHEMBL533096 | 0.85 | ALDH1A1 (0.62) | ALDH1A1ME3ABL1SMN1; SMN2MAPT | |
| SCHEMBL8143555 | 0.81 | ALDH1A1 (0.48) | ALDH1A1ME3ABL1SMN1; SMN2MAPT | |
| SCHEMBL8135054 | 0.81 | LMNA (0.49) | ALDH1A1ME3ABL1SMN1; SMN2RAB9A | |
| Acetic Acid SCHEMBL8135057 | 0.80 | ME3 (0.52) | ALDH1A1ME3ABL1SMN1; SMN2RAB9A | |
| Acetic Acid SCHEMBL7374818 | 0.79 | ALDH1A1 (0.55) | ALDH1A1ME3ABL1MAPTGAA | |
| SCHEMBL7376347 | 0.79 | ALDH1A1 (0.43) | ALDH1A1ME3ABL1SMN1; SMN2MAPT | |
| Acetic Acid SCHEMBL8143556 | 0.78 | ME3 (0.55) | ALDH1A1ME3ABL1SMN1; SMN2RAB9A | |
| SCHEMBL7370662 | 0.78 | PTPN2 (0.51) | ALDH1A1ME3ABL1SMN1; SMN2RAB9A | |
| SCHEMBL7371765 | 0.77 | ME3 (0.54) | ALDH1A1ME3ABL1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069143-A | Fibrinogen receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-30 | — | — | US | disclosed |