Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10713161 | 0.92 | L3MBTL1 (0.43) | CTSSCTSKL3MBTL1MMEACE | |
| SCHEMBL7383447 | 0.92 | ACE (0.46) | CTSSCTSLCTSBCTSKAKT1 | |
| SCHEMBL7374304 | 0.88 | MMEL1 (0.51) | L3MBTL1MMEACE | |
| SCHEMBL7373720 | 0.88 | MMEL1 (0.51) | L3MBTL1MMEACE | |
| SCHEMBL10646158 | 0.87 | KMT2A (0.45) | CTSSCTSLCTSKKMT2AMME | |
| SCHEMBL7383300 | 0.87 | MMEL1 (0.52) | CTSSCTSKL3MBTL1MMEACE | |
| SCHEMBL11072158 | 0.82 | ALDH1A1 (0.41) | CTSSCTSLCTSBCTSKALDH1A1 | |
| SCHEMBL7373739 | 0.82 | MME (0.48) | POLBALDH1A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7381161 | 0.81 | TACR1 (0.48) | POLBCTSSCTSLCTSBCTSK | |
| SCHEMBL10449998 | 0.81 | CTSL (0.40) | POLBCTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4906615-A | Substituted dipeptides as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1990-03-06 | — | — | US | disclosed |
| US-4610816-A | ANALGESICS | SCHERING CORPORATION (US) | 1986-09-09 | — | — | US | disclosed |