Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.51 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.46 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.46 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.46 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.46 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.46 |
| ▸ | GCGR | P47871 | 1/20 | 0.46 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.46 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.46 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.46 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373720 | 1.00 | MMEL1 (0.51) | MMEL1ADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL7383300 | 0.99 | MMEL1 (0.52) | MMEL1ADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL7383447 | 0.96 | ACE (0.46) | MMEL1MMEACE | |
| SCHEMBL10713161 | 0.94 | L3MBTL1 (0.43) | MMEL1ADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL10646158 | 0.91 | KMT2A (0.45) | MMEL1MMEACE | |
| SCHEMBL7377271 | 0.88 | POLB (0.40) | L3MBTL1MMEACE | |
| SCHEMBL11072416 | 0.85 | MME (0.42) | MMEL1MMEACE | |
| SCHEMBL7377272 | 0.85 | MME (0.56) | MMEACE | |
| SCHEMBL11074282 | 0.84 | CTSS (0.42) | MMEL1MMEACE | |
| SCHEMBL7375938 | 0.83 | MME (0.42) | MMEL1MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103077-B1 | SUBSTITUTED DIPEPTIDES, METHODS FOR THEIR PRODUCTION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, METHOD FOR MAKING SUCH PHARMACEUTICAL COMPOSITIONS | SCHERING CORPORATION (US) | 1988-05-18 | — | — | EP | claimed |
| EP-0103077-A2 | Substituted dipeptides, methods for their production, pharmaceutical compositions containing them, method for making such pharmaceutical compositions | SCHERING CORPORATION (US) | 1984-03-21 | — | — | EP | claimed |
| US-4906615-A | Substituted dipeptides as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1990-03-06 | — | — | US | disclosed |
| EP-0103077-B1 | SUBSTITUTED DIPEPTIDES, METHODS FOR THEIR PRODUCTION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, METHOD FOR MAKING SUCH PHARMACEUTICAL COMPOSITIONS | SCHERING CORPORATION (US) | 1988-05-18 | — | — | EP | disclosed |
| US-4721726-A | ANALGESICS | SCHERING CORPORATION (US) | 1988-01-26 | — | — | US | disclosed |
| US-4610816-A | ANALGESICS | SCHERING CORPORATION (US) | 1986-09-09 | — | — | US | disclosed |