Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | MME | P08473 | 10/20 | 0.42 |
| ▸ | ACE | P12821 | 8/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 7/20 | 0.41 |
| ▸ | CPA1 | P15085 | 6/20 | 0.40 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.38 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.38 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10449998 | 0.96 | CTSL (0.40) | CTSSCTSKACECTSLCTSB | |
| SCHEMBL7377272 | 0.87 | MME (0.56) | MMEACEACE2CPA1 | |
| SCHEMBL10647675 | 0.86 | CTSL (0.39) | CTSSCTSKACECTSLCTSB | |
| SCHEMBL11074641 | 0.84 | MME (0.48) | MMEACEACE2CPA1MMEL1 | |
| SCHEMBL10647590 | 0.84 | MME (0.48) | MMEACEACE2CPA1MMEL1 | |
| SCHEMBL10650875 | 0.84 | ALDH1A1 (0.39) | CTSSCTSKCTSLCTSB | |
| SCHEMBL7374304 | 0.84 | MMEL1 (0.51) | MMEACEMMEL1 | |
| SCHEMBL7373720 | 0.84 | MMEL1 (0.51) | MMEACEMMEL1 | |
| SCHEMBL10713161 | 0.84 | L3MBTL1 (0.43) | CTSSCTSKMMEACEACE2 | |
| SCHEMBL11072416 | 0.83 | MME (0.42) | CTSSCTSKMMEACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103077-A2 | Substituted dipeptides, methods for their production, pharmaceutical compositions containing them, method for making such pharmaceutical compositions | SCHERING CORPORATION (US) | 1984-03-21 | — | — | EP | claimed |