Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326205 | 0.79 | ALDH1A1 (0.46) | NAAARENALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL27509909 | 0.73 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2A | |
| SCHEMBL12296074 | 0.71 | CYP19A1 (0.45) | NAAANPC1ALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL15329358 | 0.70 | NPSR1 (0.44) | NAAARENNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3819580 | 0.68 | CTSK (0.52) | CA2 | |
| SCHEMBL2401238 | 0.68 | CTSK (0.52) | CA2 | |
| SCHEMBL7330719 | 0.68 | REN (0.44) | RENALDH1A1 | |
| SCHEMBL5607976 | 0.68 | NAAA (0.51) | NAAAALDH1A1EPHX2CYP19A1CA2 | |
| SCHEMBL22186518 | 0.67 | CYP19A1 (0.46) | NAAARENNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27928462 | 0.67 | ALDH1A1 (0.60) | NAAAALDH1A1SMN1; SMN2EPHX2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393457-A1 | Proteinase inhibitor | SUNTORY LIMITED (JP) | 1990-10-24 | — | — | EP | disclosed |