Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.30 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.30 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.30 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.30 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18602333 | 0.86 | SLC6A4 (0.44) | MAOA | |
| SCHEMBL12303200 | 0.86 | SLC6A4 (0.44) | MAOA | |
| SCHEMBL21415751 | 0.83 | SLC6A4 (0.43) | ESR1ESR2PBRM1MAOAMAOB | |
| SCHEMBL626140 | 0.79 | ACHE (0.44) | ESR1ESR2PBRM1GRIA4 | |
| SCHEMBL7383413 | 0.78 | PBRM1 (0.33) | PBRM1 | |
| SCHEMBL25343596 | 0.78 | ADRB2 (0.45) | ESR1ESR2PBRM1 | |
| SCHEMBL16992759 | 0.78 | ALDH1A1 (0.38) | ESR1ESR2PBRM1 | |
| SCHEMBL9451732 | 0.78 | PYCR1 (0.41) | ESR1ESR2PBRM1 | |
| SCHEMBL16992752 | 0.78 | ALDH1A1 (0.38) | ESR1ESR2PBRM1 | |
| SCHEMBL16992757 | 0.78 | ALDH1A1 (0.38) | ESR1ESR2PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997042168-A1 | THIO DERIVATIVES OF HYDROXAMIC ACIDS | ZENECA LIMITED (GB) | 1997-11-13 | — | — | WO | disclosed |