Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 10/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.52 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7377431 | 0.82 | CAPN1 (0.48) | SGMS2CAPN1ALDH1A1RAB9ASLC1A5 | |
| SCHEMBL7375746 | 0.80 | CAPN1 (0.54) | SGMS2CAPN1POLBALDH1A1RAB9A | |
| SCHEMBL7787025 | 0.77 | CAPN1 (0.52) | CAPN1ALDH1A1 | |
| SCHEMBL8034556 | 0.72 | PARP1 (0.61) | SGMS2POLBALDH1A1RAB9ASLC1A5 | |
| SCHEMBL27676596 | 0.71 | CTSS (0.49) | CAPN1 | |
| SCHEMBL30359932 | 0.70 | SGMS2 (0.54) | SGMS2POLBALDH1A1LRRK2 | |
| SCHEMBL21590052 | 0.70 | SGMS2 (0.54) | SGMS2POLBALDH1A1LRRK2 | |
| SCHEMBL19133749 | 0.70 | SGMS2 (1.00) | SGMS2ALDH1A1LRRK2 | |
| SCHEMBL30322841 | 0.70 | SGMS2 (1.00) | SGMS2ALDH1A1LRRK2 | |
| SCHEMBL15941086 | 0.69 | SGMS2 (0.55) | SGMS2CAPN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251917-B1 | Benzamidoaldehydes and their use as cysteine protease inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |
| EP-0944584-A1 | BENZAMIDOALDEHYDES AND THEIR USE AS CYSTEINE PROTEASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998023581-A1 | BENZAMIDOALDEHYDES AND THEIR USE AS CYSTEINE PROTEASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-04 | — | — | WO | disclosed |