Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2368553 | 0.87 | TSHR (0.45) | TSHRALDH1A1AOC3MEN1KMT2A | |
| SCHEMBL2368925 | 0.85 | ALDH1A1 (0.44) | TSHRALDH1A1AOC3MEN1KMT2A | |
| SCHEMBL8366080 | 0.85 | ALDH1A1 (0.44) | TSHRALDH1A1AOC3MEN1KMT2A | |
| SCHEMBL2659567 | 0.83 | TSHR (0.54) | TSHRALDH1A1AOC3CARM1PRMT6 | |
| SCHEMBL25069881 | 0.82 | TSHR (0.46) | TSHRALDH1A1AOC3CARM1PRMT6 | |
| Hydrochloric Acid SCHEMBL27321276 | 0.82 | ALDH1A1 (0.52) | TSHRALDH1A1AOC3CARM1PRMT6 | |
| SCHEMBL10477328 | 0.79 | TSHR (0.54) | TSHRALDH1A1AOC3CARM1PRMT6 | |
| SCHEMBL27360826 | 0.79 | CSNK1E (0.38) | TSHRALDH1A1AOC3ADRA2BADRA2C | |
| SCHEMBL112375 | 0.74 | TSHR (0.58) | TSHRALDH1A1AOC3CARM1PRMT6 | |
| Hydrochloric Acid SCHEMBL31556140 | 0.72 | TSHR (0.56) | TSHRALDH1A1AOC3CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101045759-B | Styrene or substituted styrene polymer type quaternary ammonium salt antistat or bacterial agent and preparation method thereof | DINGLAN GREEN CHEMICAL INST CO LTD CHANGZHOU | 2011-06-01 | — | — | CN | claimed |
| CN-101045759-A | Styrene or substituted styrene polymer type quaternary ammonium salt antistat or bacterial agent and preparation method thereof | DINGLAN GREEN CHEMICAL INST CO (CN) | 2007-10-03 | — | — | CN | claimed |
| US-8138342-B2 | 11β-hydroxysteroid dehydrogenase type 1 active spiro compounds | High Point Pharmacueticals, LLC (US) | 2012-03-20 | — | — | US | disclosed |
| CN-101045759-B | Styrene or substituted styrene polymer type quaternary ammonium salt antistat or bacterial agent and preparation method thereof | DINGLAN GREEN CHEMICAL INST CO LTD CHANGZHOU | 2011-06-01 | — | — | CN | disclosed |
| US-20090105289-A1 | 11beta-hydroxysteroid dehydrogenase type 1 active spiro compounds | NOVO NORDISK A/S (DK) | 2009-04-23 | — | — | US | disclosed |
| CN-101045759-A | Styrene or substituted styrene polymer type quaternary ammonium salt antistat or bacterial agent and preparation method thereof | DINGLAN GREEN CHEMICAL INST CO (CN) | 2007-10-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105289-A1 | 11beta-hydroxysteroid dehydrogenase type 1 active spiro compounds | HSD11B1, HSD3B1, HSD17B1 | TSHR 3273/4885ALDH1A1 53/4885AOC3 3397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.