Sugi Predict

Sugi Predict / Compounds / SCHEMBL2659567

SCHEMBL2659567

SCHEMBL2659567

CCON(C)Cc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.54
▸ ALDH1A1 P00352 2/20 0.54
▸ AOC3 Q16853 1/20 0.50
▸ NPC1 O15118 3/20 0.47
▸ RAB9A P51151 3/20 0.47
▸ CARM1 Q86X55 1/20 0.44
▸ PRMT6 Q96LA8 1/20 0.44
▸ PRMT8 Q9NR22 1/20 0.44
▸ KDM4E B2RXH2 1/20 0.43
▸ GAA P10253 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ ADRA2B P18089 1/20 0.42
▸ ADRA2C P18825 1/20 0.42
▸ SLC6A2 P23975 1/20 0.42
▸ HTR2A P28223 1/20 0.42
▸ SLC6A4 P31645 1/20 0.42
▸ ADRA1A P35348 1/20 0.42
▸ OPRK1 P41145 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27321276 0.98 ALDH1A1 (0.52) TSHRALDH1A1AOC3NPC1RAB9A
SCHEMBL738161 0.83 TSHR (0.50) TSHRALDH1A1AOC3NPC1RAB9A
SCHEMBL10477328 0.83 TSHR (0.54) TSHRALDH1A1AOC3NPC1RAB9A
SCHEMBL8423289 0.80 TSHR (0.50) TSHRALDH1A1AOC3NPC1RAB9A
SCHEMBL2368553 0.79 TSHR (0.45) TSHRALDH1A1AOC3KMT2AKCNH2
SCHEMBL27653710 0.79 TSHR (0.45) TSHRALDH1A1AOC3NPC1RAB9A
SCHEMBL8366080 0.77 ALDH1A1 (0.44) TSHRALDH1A1AOC3SMN1; SMN2KMT2A
SCHEMBL2368925 0.77 ALDH1A1 (0.44) TSHRALDH1A1AOC3SMN1; SMN2KMT2A
SCHEMBL112375 0.77 TSHR (0.58) TSHRALDH1A1AOC3NPC1RAB9A
SCHEMBL8603266 0.77 AOC3 (0.54) TSHRALDH1A1AOC3NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107189010-B A kind of preparation method of hydrophobically modified polyacrylamide 山东大学 2019-04-12 — — CN claimed
CN-108358524-A A kind of outer wall self heat-preserving brick 宁波纯恒固废科技有限公司 2018-08-03 — — CN claimed
CN-107189010-A A kind of preparation method of hydrophobically modified polyacrylamide 山东大学 2017-09-22 — — CN claimed
CN-107189010-B A kind of preparation method of hydrophobically modified polyacrylamide 山东大学 2019-04-12 — — CN disclosed
US-20170183369-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2017-06-29 — — US disclosed
US-20170107241-A1 SALEN COMPLEXES WITH DIANIONIC COUNTERIONS NOVOMER, INC. (US) 2017-04-20 — — US disclosed
US-20170080409-A1 CATALYSTS FOR EPOXIDE CARBONYLATION NOVOMER, INC. (US) 2017-03-23 — — US disclosed
CN-106398581-A Antistatic agent for adhesive 第工业制药株式会社 2017-02-15 — — CN disclosed
US-9505878-B2 Catalysts and methods for polymer synthesis NOVOMER, INC. (US) 2016-11-29 — — US disclosed
CN-105873634-A System for transdermal delivery of active substances LTS勒曼治疗系统股份公司 2016-08-17 — — CN disclosed
US-9403861-B2 Salen complexes with dianionic counterions NOVOMER, INC. (US) 2016-08-02 — — US disclosed
US-20130144032-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS NOVOMER, INC. (US) 2013-06-06 — — US disclosed
US-20130144031-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS NOVOMER, INC. (US) 2013-06-06 — — US disclosed
CN-102802781-A Polysaccharide matrix having a grafted polymer, method for producing the same and use thereof SARTORIUS STEDIM BIOTECH GMBH 2012-11-28 — — CN disclosed
CN-101454027-A Curable hydrophilic compositions 3M INNOVATIVE PROPERTIES CO (US) 2009-06-10 — — CN disclosed
CN-100374425-C Aryl and heteroaryl urea CHK1 inhibitors for use as radiosensitizers and chamosensitizers YILE LILY CO LTD (US) 2008-03-12 — — CN disclosed
CN-1638720-A Silicone elastomer emulsion cosmetic compositions comprising internal phase comprising colorant PROCTER & GAMBLE (US) 2005-07-13 — — CN disclosed
CN-1507436-A Aryl and heteroaryl urea CHK1 inhibitors for use as radiosensitizers and chamosensitizers — 2004-06-23 — — CN disclosed
US-20040097557-A1 Cyanothiophene derivatives, compositions containing such compounds and methods of use DUFFY JOSEPH L (US) 2004-05-20 — — US disclosed
CN-1395613-A Antimicrobial compositions PROCTER & GAMBLE (US) 2003-02-05 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170107241-A1 SALEN COMPLEXES WITH DIANIONIC COUNTERIONS NCLN, POLN, NCL TSHR 4704/4885ALDH1A1 3519/4885AOC3 696/4885
US-20130144032-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS PPOX, COASY, SOD1 TSHR 4849/4885ALDH1A1 2255/4885AOC3 43/4885
US-20170183369-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS PPOX, COASY, SOD1 TSHR 4849/4885ALDH1A1 2255/4885AOC3 43/4885
US-20040097557-A1 Cyanothiophene derivatives, compositions containing such compounds and methods of use GLP1R, GPR119, GCGR TSHR 106/4885ALDH1A1 2652/4885AOC3 1757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.