Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.35 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29155320 | 0.88 | SIGMAR1 (0.45) | MAPK1KMT2AL3MBTL1SIGMAR1 | |
| SCHEMBL30020659 | 0.79 | NAMPT (0.46) | ALDH1A1 | |
| SCHEMBL27675677 | 0.77 | SMN1; SMN2 (0.48) | CYP2C19TPSAB1TPSD1TPSG1MEN1 | |
| SCHEMBL22169212 | 0.76 | USP2 (0.39) | NR1H2HPGDMAPK1TPSAB1TPSD1 | |
| SCHEMBL6017362 | 0.75 | MAP4K4 (0.40) | NR1H2HTT | |
| SCHEMBL10982828 | 0.75 | USP2 (0.40) | NR1H2HPGDMAPK1TPSAB1TPSD1 | |
| SCHEMBL4359418 | 0.75 | USP2 (0.40) | NR1H2HPGDMAPK1TPSAB1TPSD1 | |
| SCHEMBL30254155 | 0.74 | ALDH1A1 (0.45) | CYP1A2MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL19143990 | 0.74 | MEN1 (0.55) | CYP1A2CYP2C9CYP2C19NR1H2MAPK1 | |
| SCHEMBL24819373 | 0.73 | SMN1; SMN2 (0.50) | HPGDTPSAB1TPSD1TPSG1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885213-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0885213-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997025323-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-17 | — | — | WO | disclosed |