Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29155320 | 0.85 | SIGMAR1 (0.45) | GPR119HTR6KDM4E | |
| SCHEMBL7383181 | 0.79 | CYP3A4 (0.40) | ALDH1A1 | |
| SCHEMBL30254155 | 0.77 | ALDH1A1 (0.45) | GPR119FDPSALDH1A1KDM4E | |
| SCHEMBL28310399 | 0.76 | FDPS (0.49) | FDPSALDH1A1KDM4EBTN3A1PDE3A | |
| SCHEMBL29465171 | 0.76 | NAPRT (0.51) | FDPSALDH1A1KDM4EBTN3A1PDE3A | |
| SCHEMBL4234534 | 0.76 | FNTA (0.57) | NAMPTGPR119ALDH1A1KDM4EKIT | |
| SCHEMBL3581351 | 0.75 | FNTA (0.62) | MKNK1MKNK2ALDH1A1KDM4E | |
| SCHEMBL29795260 | 0.75 | CYP1A2 (0.49) | FDPSALDH1A1KDM4EBTN3A1PDE3A | |
| SCHEMBL29958765 | 0.75 | FNTA (0.62) | MKNK1MKNK2ALDH1A1KDM4E | |
| SCHEMBL27504718 | 0.75 | CYP1A2 (0.49) | FDPSALDH1A1KDM4EBTN3A1PDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279770-A | Compounds and compositions for treating diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2022-11-01 | — | — | CN | disclosed |