Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4360123 | 0.81 | FAAH (0.38) | MAPK1GRM5 | |
| SCHEMBL29155320 | 0.81 | SIGMAR1 (0.45) | KDM4EGPR119MAPK1L3MBTL1POLB | |
| SCHEMBL4363957 | 0.81 | P2RY12 (0.41) | MAPK1 | |
| SCHEMBL30020659 | 0.77 | NAMPT (0.46) | ALDH1A1KDM4EGPR119FDPS | |
| 2-Aminopyridine SCHEMBL28404259 | 0.77 | GPR119 (0.53) | GPR119MAPK1POLBGRM5 | |
| 2-Picolinic Acid SCHEMBL28101337 | 0.76 | GPR119 (0.52) | KDM4EGPR119MAPK1L3MBTL1POLB | |
| 2-Pyridinecarboxaldehyde SCHEMBL6182995 | 0.75 | GPR119 (0.51) | GPR119MAPK1POLBGRM5 | |
| SCHEMBL28863731 | 0.75 | GPR119 (0.51) | KDM4EGPR119MAPK1POLBGRM5 | |
| SCHEMBL29638860 | 0.74 | FDPS (0.46) | ALDH1A1MAPK1TSHRL3MBTL1CYP1A2 | |
| SCHEMBL7383181 | 0.74 | CYP3A4 (0.40) | ALDH1A1MAPK1L3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112154145-B | Piperazine azaspiro derivatives | 辉瑞大药厂 | 2023-10-17 | — | — | CN | disclosed |
| CN-115697990-A | Indazole-based compounds and related methods of use | 阿维纳斯企业公司 | 2023-02-03 | — | — | CN | disclosed |