Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 6/20 | 0.49 |
| ▸ | MMP13 | P45452 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MMP7 | P09237 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510019 | 0.88 | MMP9 (0.60) | MMP1MMP13ALDH1A1MMP9MAPT | |
| SCHEMBL6501997 | 0.85 | MMP13 (0.58) | MMP1MMP13ALDH1A1MMP9MAPT | |
| SCHEMBL27451020 | 0.72 | ALDH1A1 (0.55) | MMP1MMP13ALDH1A1MMP9CYP3A4 | |
| SCHEMBL6501553 | 0.71 | ADAMTS4 (0.57) | MMP1MMP13MMP9MAPTMMP2 | |
| SCHEMBL6500454 | 0.70 | MMP13 (0.58) | MMP1MMP13MMP9MAPTMMP2 | |
| SCHEMBL7744256 | 0.70 | MMP13 (0.55) | MMP1MMP13ALDH1A1MAPTCYP1A2 | |
| SCHEMBL7075250 | 0.70 | MMP13 (0.59) | MMP1MMP13ALDH1A1MMP9MMP2 | |
| SCHEMBL7273970 | 0.69 | HTT (0.55) | MMP1MMP13ALDH1A1MMP8HTT | |
| SCHEMBL6723666 | 0.69 | MMP9 (0.72) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL5839717 | 0.69 | MMP9 (0.92) | MMP1MMP13MMP9MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083112-A2 | METHOD FOR THE TREATMENT OF POLYCYSTIC KIDNEY DISEASE | WYETH HOLDINGS CORPORATION (US) | 2002-10-24 | — | — | WO | disclosed |