Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7388218 | 0.86 | ALDH1A1 (0.62) | SMN1; SMN2NPC1ALDH1A1LMNAGAA | |
| SCHEMBL7387080 | 0.84 | SIGMAR1 (0.63) | SMN1; SMN2ALDH1A1LMNAGAAMAPT | |
| SCHEMBL7386301 | 0.84 | LMNA (0.60) | SMN1; SMN2ALDH1A1LMNAGAAMAPT | |
| SCHEMBL7392283 | 0.83 | CCR3 (0.59) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL7384798 | 0.82 | CCR3 (0.58) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL7395714 | 0.81 | NPC1 (0.60) | SMN1; SMN2NPC1ALDH1A1LMNAGAA | |
| SCHEMBL7386884 | 0.80 | POLB (0.58) | SMN1; SMN2NPC1ALDH1A1LMNAGAA | |
| SCHEMBL7389102 | 0.80 | DRD2 (0.60) | SMN1; SMN2ALDH1A1LMNAGAAMAPT | |
| SCHEMBL7387157 | 0.78 | HPGD (0.54) | SMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL7388016 | 0.78 | ALDH1A1 (0.69) | SMN1; SMN2ALDH1A1LMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0774460-A1 | BENZOIC ACID COMPOUND AND USE THEREOF AS MEDICINE | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-05-21 | — | — | EP | disclosed |