Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7381321 | 0.82 | GAA (0.51) | LMNAHTTL3MBTL1GAAMEN1 | |
| SCHEMBL7379862 | 0.82 | GAA (0.51) | LMNAHTTL3MBTL1GAAMEN1 | |
| SCHEMBL7384133 | 0.82 | GAA (0.51) | LMNAHTTL3MBTL1GAAMEN1 | |
| SCHEMBL23969551 | 0.80 | LMNA (0.44) | LMNAHTTGAAMEN1KMT2A | |
| SCHEMBL13706557 | 0.80 | ALDH1A1 (0.44) | LMNAGAAMEN1KMT2AKDM4E | |
| SCHEMBL30731578 | 0.80 | LMNA (0.44) | LMNAHTTGAAMEN1KMT2A | |
| SCHEMBL13479816 | 0.80 | ALDH1A1 (0.45) | LMNAL3MBTL1MEN1KMT2AADRA1A | |
| SCHEMBL29439746 | 0.76 | LMNA (0.45) | LMNAHTTGAAKMT2AMAPT | |
| SCHEMBL3676819 | 0.76 | LMNA (0.45) | LMNAHTTGAAKMT2AMAPT | |
| SCHEMBL28658416 | 0.76 | HTR1A (0.56) | LMNAGAAMEN1KMT2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281617-A | Enzyme inhibitor | CORTECH, INC. (US) | 1994-01-25 | — | — | US | claimed |
| US-5281617-A | Enzyme inhibitor | CORTECH, INC. (US) | 1994-01-25 | — | — | US | disclosed |