Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4Z1 | Q86W10 | 3/20 | 0.48 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.46 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | PPIB | P23284 | 1/20 | 0.39 |
| ▸ | PPIA | P62937 | 1/20 | 0.39 |
| ▸ | PPID | Q08752 | 1/20 | 0.39 |
| ▸ | PPIG | Q13427 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7385812 | 0.84 | S1PR1 (0.49) | KMT2AS1PR1 | |
| SCHEMBL7387496 | 0.81 | ITGB3 (0.54) | CYP4Z1CYP4F11CYP4F12ALDH1A1POLB | |
| SCHEMBL7383875 | 0.80 | CYP4Z1 (0.39) | CYP4Z1CYP4F11CYP4F12ALDH1A1MAPK1 | |
| SCHEMBL7385708 | 0.79 | TSHR (0.53) | POLBKMT2A | |
| SCHEMBL8995555 | 0.76 | MEN1 (0.55) | ALDH1A1KMT2A | |
| SCHEMBL7386535 | 0.75 | ITGB3 (0.49) | CYP4Z1CYP4F11CYP4F12ALDH1A1MAPK1 | |
| SCHEMBL7386038 | 0.75 | TSHR (0.42) | POLB | |
| SCHEMBL7353561 | 0.74 | LMNA (0.49) | ALDH1A1GAATDP1KMT2A | |
| SCHEMBL7384441 | 0.74 | EPHX2 (0.49) | ALDH1A1KMT2A | |
| SCHEMBL12341372 | 0.74 | EPHX2 (0.56) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344837-A | Platelet aggregation inhibitors | G.D. SEARLE & CO. (US) | 1994-09-06 | — | — | US | disclosed |
| WO-1994001396-A1 | PHENYL AMIDINE UREA DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-01-20 | — | — | WO | disclosed |
| US-5272162-A | Platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1993-12-21 | — | — | US | disclosed |