Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7383875 | 0.88 | CYP4Z1 (0.39) | EPHX2ALDH1A1KMT2A | |
| SCHEMBL7384441 | 0.83 | EPHX2 (0.49) | EPHX2ITGB3ITGA2BALDH1A1HPGD | |
| SCHEMBL7387824 | 0.82 | ITGB3 (0.56) | ITGB3ITGA2B | |
| SCHEMBL7385683 | 0.80 | EPHX2 (0.54) | EPHX2ITGB3ITGA2BALDH1A1HPGD | |
| SCHEMBL7385812 | 0.78 | S1PR1 (0.49) | EPHX2ITGB3ITGA2BKMT2A | |
| SCHEMBL8995559 | 0.76 | KMT2A (0.44) | ALDH1A1HPGDKMT2A | |
| SCHEMBL7386330 | 0.75 | EPHX2 (0.43) | EPHX2ITGB3ITGA2B | |
| SCHEMBL7378676 | 0.75 | ITGB3 (0.49) | ITGB3ITGA2BALDH1A1HPGDKMT2A | |
| SCHEMBL7382281 | 0.74 | ITGB3 (0.47) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL7389607 | 0.74 | ITGB3 (0.50) | ITGB3ITGA2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344837-A | Platelet aggregation inhibitors | G.D. SEARLE & CO. (US) | 1994-09-06 | — | — | US | disclosed |
| WO-1994001396-A1 | PHENYL AMIDINE UREA DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-01-20 | — | — | WO | disclosed |
| US-5272162-A | Platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1993-12-21 | — | — | US | disclosed |