Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384441 | 0.84 | EPHX2 (0.49) | KMT2AALDH1A1HPGD | |
| SCHEMBL8995540 | 0.81 | KMT2A (0.38) | KMT2AALDH1A1HPGDCYP2D6CYP2C9 | |
| SCHEMBL7418987 | 0.81 | LMNA (0.41) | KMT2AALDH1A1HPGDCYP2D6CYP2C9 | |
| SCHEMBL7424911 | 0.79 | PSMB8 (0.45) | ALDH1A1HPGD | |
| SCHEMBL8995543 | 0.79 | ITGB3 (0.61) | KMT2AALDH1A1HPGD | |
| SCHEMBL8995552 | 0.79 | ITGB3 (0.61) | KMT2AALDH1A1HPGD | |
| SCHEMBL7385812 | 0.78 | S1PR1 (0.49) | KMT2ALMNAS1PR1TSHR | |
| SCHEMBL7423101 | 0.78 | S1PR2 (0.38) | KMT2ACYP2D6CYP2C9CYP2C19LMNA | |
| SCHEMBL7385683 | 0.77 | EPHX2 (0.54) | KMT2AALDH1A1HPGD | |
| SCHEMBL7417109 | 0.77 | CASP1 (0.52) | CASP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552431-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-09-03 | — | — | US | disclosed |
| US-5424334-A | Peptide mimetic compounds useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-06-13 | — | — | US | disclosed |