Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16075830 | 0.76 | ALDH1A1 (0.39) | ALDH1A1OPRM1MEN1KMT2AATM | |
| SCHEMBL762290 | 0.74 | — | — | |
| SCHEMBL19601333 | 0.74 | ALDH1A1 (0.37) | ALDH1A1OPRM1MEN1KMT2AATM | |
| SCHEMBL3978891 | 0.74 | FFAR3 (0.31) | — | |
| SCHEMBL740872 | 0.72 | CTSL (0.35) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9313190 | 0.71 | DGAT1 (0.41) | ALDH1A1OPRM1ATMALOX15MAPT | |
| SCHEMBL17682117 | 0.69 | MAPT (0.37) | ALDH1A1OPRM1ATMMAPTPOLB | |
| SCHEMBL11372937 | 0.68 | SMN1; SMN2 (0.37) | ALDH1A1TSHROPRM1MEN1KMT2A | |
| SCHEMBL4153304 | 0.68 | POLB (0.33) | ALDH1A1OPRM1MEN1KMT2AATM | |
| SCHEMBL4671893 | 0.68 | GAA (0.38) | ALDH1A1OPRM1KDM4EPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8378119-B2 | Method for producing asymmetric tetrasubstituted carbon atom-containing compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-02-19 | — | — | US | disclosed |
| EP-1970669-B1 | Self-calibration of scale factor for dual resonator class II coriolis vibratory gyros | LITTON SYSTEMS INC (US) | 2012-08-01 | — | — | EP | disclosed |
| US-20120172605-A1 | METHOD FOR PRODUCING ASYMMETRIC TETRASUBSTITUTED CARBON ATOM-CONTAINING COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-07-05 | — | — | US | disclosed |
| US-8138352-B2 | Method for producing asymmetric tetrasubstituted carbon atom-containing compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |
| US-8136382-B2 | Self-calibration of scale factor for dual resonator class II Coriolis vibratory gyros | NORTHROP GRUMMAN GUIDANCE AND ELECTRONICS COMPANY, INC. (US) | 2012-03-20 | — | — | US | disclosed |
| US-20110144339-A1 | METHOD FOR PRODUCING ASYMMETRIC TETRASUBSTITUTED CARBON ATOM-CONTAINING COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-06-16 | — | — | US | disclosed |
| US-7928232-B2 | Method for producing asymmetric tetrasubstituted carbon atom-containing compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-04-19 | — | — | US | disclosed |
| US-20100218587-A1 | Self-calibration of scale factor for dual resonator class II coriolis vibratory gyros | STEWART ROBERT E | 2010-09-02 | — | — | US | disclosed |
| US-7739896-B2 | Self-calibration of scale factor for dual resonator class II coriolis vibratory gyros | NORTHROP GRUMMAN GUIDANCE AND ELECTRONICS COMPANY, INC. (US) | 2010-06-22 | — | — | US | disclosed |
| US-20090054648-A1 | METHOD FOR PRODUCING ASYMMETRIC TETRASUBSTITUTED CARBON ATOM-CONTAINING COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-02-26 | — | — | US | disclosed |
| US-20080223107-A1 | Self-calibration of scale factor for dual resonator class II coriolis vibratory gyros | LITTON SYSTEMS INC. | 2008-09-18 | — | — | US | disclosed |
| EP-1970669-A2 | Self-calibration of scale factor for dual resonator class II coriolis vibratory gyros | LITTON SYSTEMS, INC. (US) | 2008-09-17 | — | — | EP | disclosed |
| EP-1882685-A1 | METHOD FOR PRODUCING ASYMMETRIC TETRASUBSTITUTED CARBON ATOM-CONTAINING COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2008-01-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172605-A1 | METHOD FOR PRODUCING ASYMMETRIC TETRASUBSTITUTED CARBON ATOM-CONTAINING COMPOUND | DHPS, COASY, NQO2 | ALDH1A1 1679/4885TSHR 3042/4885OPRM1 3694/4885 |
| US-20110144339-A1 | METHOD FOR PRODUCING ASYMMETRIC TETRASUBSTITUTED CARBON ATOM-CONTAINING COMPOUND | ACSL3, NQO2, COASY | ALDH1A1 1202/4885TSHR 3648/4885OPRM1 3183/4885 |
| US-20090054648-A1 | METHOD FOR PRODUCING ASYMMETRIC TETRASUBSTITUTED CARBON ATOM-CONTAINING COMPOUND | ACSL3, ARL1, NQO2 | ALDH1A1 614/4885TSHR 2836/4885OPRM1 2105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.