Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 4/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2162138 | 0.98 | MAPT (0.35) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL30446337 | 0.86 | MAPT (0.39) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL4582755 | 0.83 | ALDH1A1 (0.37) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL7195717 | 0.81 | ALDH1A1 (0.35) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL3142467 | 0.81 | ALDH1A1 (0.35) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL28346195 | 0.79 | MAPT (0.41) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL9885900 | 0.78 | GPR84 (0.39) | MAPTFAAH | |
| SCHEMBL11256547 | 0.73 | MAPT (0.37) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL20998436 | 0.73 | FDPS (0.35) | MAPTALDH1A1FAAHMGLLFDPS | |
| SCHEMBL20998429 | 0.73 | FDPS (0.35) | MAPTALDH1A1FAAHMGLLFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0989982-A1 | BARBITURIC ACID DERIVATIVES WITH ANTIMETASTATIC AND ANTITUMOR ACTIVITY | Roche Diagnostics GmbH (DE) | 2000-04-05 | — | — | EP | disclosed |
| WO-1998058925-A1 | BARBITURIC ACID DERIVATIVES WITH ANTIMETASTATIC AND ANTITUMOR ACTIVITY | ROCHE DIAGNOSTICS GMBH (DE) | 1998-12-30 | — | — | WO | disclosed |