Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | SLC40A1 | Q9NP59 | 9/20 | 0.64 |
| ▸ | MMP2 | P08253 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.62 |
| ▸ | RELA | Q04206 | 1/20 | 0.62 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5072751 | 0.89 | MEN1 (0.71) | MEN1KMT2AGAASLC40A1MMP2 | |
| SCHEMBL5074828 | 0.88 | MEN1 (0.70) | MEN1KMT2AGAASLC40A1MMP2 | |
| SCHEMBL1891388 | 0.85 | L3MBTL1 (0.54) | MEN1KMT2AGAASLC40A1TDP1 | |
| SCHEMBL8337625 | 0.85 | MEN1 (0.62) | MEN1KMT2AGAASLC40A1MMP2 | |
| SCHEMBL30854809 | 0.82 | SLC40A1 (0.76) | MEN1KMT2AGAASLC40A1MMP2 | |
| SCHEMBL1507919 | 0.82 | SLC40A1 (0.76) | MEN1KMT2AGAASLC40A1MMP2 | |
| SCHEMBL7896798 | 0.82 | SLC40A1 (0.80) | MEN1KMT2AGAASLC40A1MMP2 | |
| SCHEMBL3780950 | 0.82 | GAA (0.76) | MEN1KMT2AGAASLC40A1MMP2 | |
| SCHEMBL7571584 | 0.82 | SLC40A1 (0.66) | MEN1KMT2AGAASLC40A1MMP2 | |
| SCHEMBL30925457 | 0.81 | SLC40A1 (0.59) | MEN1KMT2ASLC40A1TDP1NFKBIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073632-A1 | SUBSTITUTED BENZAMIDES, THEIR PRODUCTION AND THEIR USE AS CYSTEINE PROTEASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999054293-A1 | SUBSTITUTED BENZAMIDES, THEIR PRODUCTION AND THEIR USE AS CYSTEINE PROTEASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-28 | — | — | WO | disclosed |